The US now has more confirmed cases of coronavirus than any other country with at least 82,404 positive tests, APA reports.
According to the latest figures collated by Johns Hopkins University, the US overtook China (81,782 cases) and Italy (80,589).
The grim milestone came as President Donald Trump predicted the nation would get back to work "pretty quickly", after 3.3 million layoffs.
More than 1,100 people with Covid-19 have died in the US.
After first appearing in Wuhan, China, in December, the virus, officially known as COVID-19, has spread to at least 198 countries and regions, according to data compiled by U.S.-based Johns Hopkins University.
The data shows more than 525,000 cases have been reported worldwide, with the death toll over 23,700 and around 123,000 recoveries.
Italy, China, Iran, and Spain continue to be the most affected countries.
Despite the rising number of cases, a vast majority of those infected with the virus suffer mild symptoms and recover.